Structure of PDB 4z3c Chain C

Receptor sequence
>4z3cC (length=44) Species: 9606 (Homo sapiens) [Search protein sequence]
KRKRCGTCEPCRRLENCGACTSCTNRRTHQICKLRKCEVLKKKV
3D structure
PDB4z3c DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.
ChainC
Resolution1.57 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.11.80: methylcytosine dioxygenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C K53 R54 H81 I83 K88 L92 K1 R2 H29 I31 K36 L40 PDBbind-CN: Kd=2.4uM
BS02 dna C K53 T73 N77 T80 H81 Q82 K1 T21 N25 T28 H29 Q30 PDBbind-CN: Kd=2.4uM
BS03 ZN C C57 C60 C63 C89 C5 C8 C11 C37
BS04 ZN C C69 C72 C75 C84 C17 C20 C23 C32
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:4z3c, PDBe:4z3c, PDBj:4z3c
PDBsum4z3c
PubMed29276034
UniProtO43151|TET3_HUMAN Methylcytosine dioxygenase TET3 (Gene Name=TET3)

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