Structure of PDB 4yb7 Chain C

Receptor sequence
>4yb7C (length=294) Species: 195099 (Campylobacter jejuni RM1221) [Search protein sequence]
NTRLRIAIQKSGRLSKESIELLSECGVKMHIHEQSLIAFSTNLPIDILRV
RDDDIPGLIFDGVVDLGIIGENVLEENELERQSLGENPSYKLLKKLDFGY
CRLSLALPQENKFQNLKDFEGLRIATSYPQLLKRFMKENGINYKNCTLTG
SVEVAPRANLADAICDLVSSGATLQANNLKEVKVIYESRACLIQKENALS
KEKQALVDKIMLRVAGVMQARESKYIMLHAPKEKLDKIQALLPGVERPTI
LPLDEKNVALHMVSKENLFWETMEALKEEGASSILVLPIEKMLK
3D structure
PDB4yb7 Campylobacter jejuni adenosine triphosphate phosphoribosyltransferase is an active hexamer that is allosterically controlled by the twisting of a regulatory tail.
ChainC
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.2.17: ATP phosphoribosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG C D55 D56 D52 D53
BS02 PO4 C V171 S172 S173 G174 T176 V168 S169 S170 G171 T173
BS03 ATP C Q12 G15 R16 R54 D55 N75 C104 L170 S172 Q9 G12 R13 R51 D52 N72 C101 L167 S169 PDBbind-CN: -logKd/Ki=3.80,Kd=158uM
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003879 ATP phosphoribosyltransferase activity
GO:0005524 ATP binding
GO:0016757 glycosyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0000105 L-histidine biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4yb7, PDBe:4yb7, PDBj:4yb7
PDBsum4yb7
PubMed27191057
UniProtQ5HSJ4|HIS1_CAMJR ATP phosphoribosyltransferase (Gene Name=hisG)

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