Structure of PDB 4y90 Chain C

Receptor sequence
>4y90C (length=244) Species: 243230 (Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539) [Search protein sequence]
MQTLLALNWKMNKTPTEARSWAEELTTKYAPAEGVDLAVLAPALDLSALA
ANLPAGIAFGGQDVSAHESGAYTGEISAAMLKDAGASCVVVGHSERREYH
DESDATVAAKARQAQANGLLPIVCVGENLDVRERGEHVPQTLAQLRGSLE
GVGADVVVAYEPVWAIGTGKTATADDAEELAAAIRGALREQYGARAEGIR
VLYGGSVKPENIAEICGKPNVNGALVGGASLKVPDVLGMLDALR
3D structure
PDB4y90 Reversibility and two state behaviour in the thermal unfolding of oligomeric TIM barrel proteins.
ChainC
Resolution2.1 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) N11 K13 H96 E98 E164 G170 S209
Catalytic site (residue number reindexed from 1) N8 K10 H93 E95 E161 G167 S206
Enzyme Commision number 5.3.1.1: triose-phosphate isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA C E78 K113 E75 K110
Gene Ontology
Molecular Function
GO:0004807 triose-phosphate isomerase activity
GO:0016853 isomerase activity
Biological Process
GO:0006094 gluconeogenesis
GO:0006096 glycolytic process
GO:0019563 glycerol catabolic process
GO:0046166 glyceraldehyde-3-phosphate biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:4y90, PDBe:4y90, PDBj:4y90
PDBsum4y90
PubMed26206330
UniProtQ9RUP5|TPIS_DEIRA Triosephosphate isomerase (Gene Name=tpiA)

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