Structure of PDB 4y60 Chain C

Receptor sequence
>4y60C (length=76) Species: 10090 (Mus musculus) [Search protein sequence]
GLRIRRPMNAFMVWAKDERKRLAQQNPDLHNAVLSKMLGKAWKELNTAEK
RPFVEEAERLRVQHLRDHPNYKYRPR
3D structure
PDB4y60 Structure and decoy-mediated inhibition of the SOX18/Prox1-DNA interaction.
ChainC
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna C R5 N8 F10 A31 S34 K35 W41 K42 Y72 R73 R6 N9 F11 A32 S35 K36 W42 K43 Y73 R74 PDBbind-CN: Kd=6.1nM
BS02 dna C R2 R4 R5 M7 M11 K15 R18 N30 Y72 R75 R3 R5 R6 M8 M12 K16 R19 N31 Y73 R76 PDBbind-CN: Kd=6.1nM
External links
PDB RCSB:4y60, PDBe:4y60, PDBj:4y60
PDBsum4y60
PubMed26939885
UniProtP43680|SOX18_MOUSE Transcription factor SOX-18 (Gene Name=Sox18)

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