Structure of PDB 4xnw Chain C

Receptor sequence
>4xnwC (length=350) Species: 1501,9606 [Search protein sequence]
SSFKCALTKTGFQFYYLPAVYILVFIIGFLGNSVAIWMFVFHMKPWSGIS
VYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDAMCKLQRFIFHVNLYG
SILFLTCISAHRYSGVVYPLKSLGRLKKKNAICISVLVWLIVVVAISPIL
FYSGTGVRKNKTITCYDTTSDEYLRSYFIYSMCTTVAMFCVPLVLILGCY
GLIVRALIYKMKKYTCTVCGYIYNPEDGDPDNGVNPGTDFKDIPDDWVCP
LCGVGKDQFEEVEEPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARL
DFQTPAMCAFNDRVYATYQVTRGLASLNSCVNPILYFLAGDTFRRRLSRA
3D structure
PDB4xnw Two disparate ligand-binding sites in the human P2Y1 receptor
ChainC
Resolution2.7 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 2ID C C42 K46 R195 D204 T205 N283 R287 Q291 Y303 Y306 C5 K9 R158 D167 T168 N295 R299 Q303 Y315 Y318
BS02 ZN C C1006 C1009 C1039 C1042 C216 C219 C249 C252
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0005506 iron ion binding
GO:0009055 electron transfer activity
GO:0045028 G protein-coupled purinergic nucleotide receptor activity
GO:0046872 metal ion binding
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
GO:0030168 platelet activation
GO:0043448 alkane catabolic process
GO:0090075 relaxation of muscle
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4xnw, PDBe:4xnw, PDBj:4xnw
PDBsum4xnw
PubMed25822790
UniProtP00268|RUBR_CLOPA Rubredoxin;
P47900|P2RY1_HUMAN P2Y purinoceptor 1 (Gene Name=P2RY1)

[Back to BioLiP]