Structure of PDB 4xaj Chain C

Receptor sequence
>4xajC (length=568) Species: 9606,83333 [Search protein sequence]
KIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQV
AATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYN
GKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFN
LQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIK
NKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTF
KGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLG
AVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINA
ASGRQTVDEALKDAQTNAAAEFTESVCESAARLLFMSIKWAKSVPAFSTL
SLQDQLMLLEDAWRELFVLGIAQWAIPVDANTLLAVSGMNGDNTDSQRLT
LIISEIQALQEVVARFRQLRLDATEFACLKCIVTFKAVPTLRSFRNAAAI
AALQDEAQLTLNSYIHTRYPTQPVRFGKLLLLLPALRSISPSTIEEVFFK
KTIGNVPITRLLSDMYKS
3D structure
PDB4xaj Structural basis for corepressor assembly by the orphan nuclear receptor TLX.
ChainC
Resolution3.551 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C E1183 C1186 E1187 A1190 F1363 K1365 T1366 L1376 Y1380 E374 C377 E378 A381 F549 K551 T552 L562 Y566
BS02 GLC C D16 K17 E113 Y157 D14 K15 E111 Y155
BS03 GLC C E46 W64 D67 E155 P156 Y157 E44 W62 D65 E153 P154 Y155
Gene Ontology
Molecular Function
GO:0015144 carbohydrate transmembrane transporter activity
Biological Process
GO:0008643 carbohydrate transport
GO:0055085 transmembrane transport

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4xaj, PDBe:4xaj, PDBj:4xaj
PDBsum4xaj
PubMed25691470
UniProtP0AEX9|MALE_ECOLI Maltose/maltodextrin-binding periplasmic protein (Gene Name=malE);
Q9Y466

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