Structure of PDB 4x4p Chain C

Receptor sequence
>4x4pC (length=434) Species: 224325 (Archaeoglobus fulgidus DSM 4304) [Search protein sequence]
VEEILEKALELVIPDEEEVRKGREAEEELRRRLDELGVEYVFVGSYARNT
WLKGSLEIDVFLLFPEEFSKEELRERGLEIGKAVLDSYEIRYAHPYVHGV
VKGVEVDVVPCYKLKEPKNIKSAVDRTPFHHKWLEGRIKGKENEVRLLKG
FLKANGIYGAEYKVRGFSGYLCELLIVFYGSFLETVKNARRWTRRTVIDV
AKGEVRKGEEFFVVDPVDEKRNVAANLSLDNLARFVHLCREFMEAPSLGF
FKPKHPLEIEPERLRKIVEERGTAVFAVKFRKPDIVDDNLYPQLERASRK
IFEFLERENFMPLRSAFKASEEFCYLLFECQIKEISRVFRRMGPQFEDER
NVKKFLSRNRAFRPFIENGRWWAFEMRKFTTPEEGVRSYASTHWHTLGKN
VGESIREYFEIISGEKLFKEPVTAELCEMMGVKD
3D structure
PDB4x4p On-Enzyme Refolding Permits Small RNA and tRNA Surveillance by the CCA-Adding Enzyme.
ChainC
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.72: CCA tRNA nucleotidyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna C A95 Y165 R224 A228 N229 D291 N292 Q296 R299 M345 P347 N354 K357 F358 R361 H396 H398 T399 K402 A93 Y162 R221 A225 N226 D288 N289 Q293 R296 M342 P344 N351 K354 F355 R358 H393 H395 T396 K399
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0000287 magnesium ion binding
GO:0003723 RNA binding
GO:0004810 CCA tRNA nucleotidyltransferase activity
GO:0005524 ATP binding
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
GO:0160016 CCACCA tRNA nucleotidyltransferase activity
Biological Process
GO:0001680 tRNA 3'-terminal CCA addition
GO:0008033 tRNA processing
GO:0031123 RNA 3'-end processing
GO:0042245 RNA repair
GO:0106354 tRNA surveillance

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4x4p, PDBe:4x4p, PDBj:4x4p
PDBsum4x4p
PubMed25640237
UniProtO28126|CCA_ARCFU CCA-adding enzyme (Gene Name=cca)

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