Structure of PDB 4x23 Chain C

Receptor sequence
>4x23C (length=102) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
SRSNRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYLAAVMEYLAAEVLEL
AGNAARDNKKTRIIPRHLQLAIRNDEELNKLLSGVTIAQGGVLPNIQAVL
LP
3D structure
PDB4x23 A conserved mechanism for centromeric nucleosome recognition by centromere protein CENP-C.
ChainC
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C R16 R19 R28 R31 R41 R76 R2 R5 R14 R17 R27 R62 PDBbind-CN: Kd=0.1uM
BS02 dna C R34 R41 V42 A44 K74 T75 R76 R20 R27 V28 A30 K60 T61 R62 PDBbind-CN: Kd=0.1uM
BS03 peptide C E60 D89 E90 E46 D75 E76
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:4x23, PDBe:4x23, PDBj:4x23
PDBsum4x23
PubMed23723239
UniProtP84051|H2A_DROME Histone H2A (Gene Name=His2A)

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