Structure of PDB 4x13 Chain C

Receptor sequence
>4x13C (length=257) Species: 804310 (JC polyomavirus type 3) [Search protein sequence]
VEVLEVKTGVDSITEVECFLTPEMGDPDEHLRGFSKSISISDTFESDSPN
KDMLPCYSVARIPLPNLILMWEAVTLKTEVIGVTTLMNVHSNGQATHDNG
AAKPVQGTSFHFFSVGGEALELQGVVFNYRTTYPDGTIFPKNATVQSQVM
NTEHKAYLDKNKAYPVECWVPDPTRNENTRYFGTLTGGENVPPVLHITNT
ATTVLLDEFGVGPLCKGDNLYLSAVDVCGMFTNRSGSQQWRGLSRYFKVQ
LRKRRVK
3D structure
PDB4x13 The Greater Affinity of JC Polyomavirus Capsid for alpha 2,6-Linked Lactoseries Tetrasaccharide c than for Other Sialylated Glycans Is a Major Determinant of Infectivity.
ChainC
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SIA C L54 K59 S60 N264 S266 S268 Q270 L31 K36 S37 N233 S235 S237 Q239 PDBbind-CN: -logKd/Ki=3.30,Kd=0.5mM
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
Cellular Component
GO:0019028 viral capsid

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Molecular Function
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Cellular Component
External links
PDB RCSB:4x13, PDBe:4x13, PDBj:4x13
PDBsum4x13
PubMed25855729
UniProtP90498

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