Structure of PDB 4x10 Chain C

Receptor sequence
>4x10C (length=257) Species: 804310 (JC polyomavirus type 3) [Search protein sequence]
EVLEVKTGVDSITEVECFLTPEMGDPDEHLRGFSKSISISDTFESDSPNK
DMLPCYSVARIPLPNLNILMWEAVTLKTEVIGVTTLMNVHSNGQATHDNG
AAKPVQGTSFHFFSVGGEALELQGVVFNYRTTYPDGTIFPKNATVQSQVM
NTEHKAYLDKNKAYPVECWVPDPTRNENTRYFGTLTGGENVPPVLHITNT
ATTVLLDEFGVGPLCKGDNLYLSAVDVCGMFTNRSGSQQWRGLSRYFKVQ
LRKRRVK
3D structure
PDB4x10 The Greater Affinity of JC Polyomavirus Capsid for alpha 2,6-Linked Lactoseries Tetrasaccharide c than for Other Sialylated Glycans Is a Major Determinant of Infectivity.
ChainC
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 SIA C L54 K59 S60 N264 S266 S268 Q270 L30 K35 S36 N233 S235 S237 Q239
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
Cellular Component
GO:0019028 viral capsid

View graph for
Molecular Function

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Cellular Component
External links
PDB RCSB:4x10, PDBe:4x10, PDBj:4x10
PDBsum4x10
PubMed25855729
UniProtP90498

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