Structure of PDB 4x0z Chain C

Receptor sequence
>4x0zC (length=256) Species: 804310 (JC polyomavirus type 3) [Search protein sequence]
EVLEVKTGVDSITEVECFLTPEMGDPDEHLRGFSKSISISDTFESDSPNK
DMLPCYSVARIPLPNLILMWEAVTLKTEVIGVTTLMNVHSNGQATHDNGA
AKPVQGTSFHFFSVGGEALELQGVVFNYRTTYPDGTIFPKNATVQSQVMN
TEHKAYLDKNKAYPVECWVPDPTRNENTRYFGTLTGGENVPPVLHITNTA
TTVLLDEFGVGPLCKGDNLYLSAVDVCGMFTNRSGSQQWRGLSRYFKVQL
RKRRVK
3D structure
PDB4x0z The Greater Affinity of JC Polyomavirus Capsid for alpha 2,6-Linked Lactoseries Tetrasaccharide c than for Other Sialylated Glycans Is a Major Determinant of Infectivity.
ChainC
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GAL C I61 S62 I37 S38 PDBbind-CN: -logKd/Ki=3.15,Kd=0.7mM
BS02 SIA C L54 K59 S60 N264 S266 S268 Q270 L30 K35 S36 N232 S234 S236 Q238 PDBbind-CN: -logKd/Ki=3.15,Kd=0.7mM
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
Cellular Component
GO:0019028 viral capsid

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:4x0z, PDBe:4x0z, PDBj:4x0z
PDBsum4x0z
PubMed25855729
UniProtP90498

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