Structure of PDB 4ww0 Chain C

Receptor sequence
>4ww0C (length=412) Species: 224324 (Aquifex aeolicus VF5) [Search protein sequence]
IEEKPKVTFKDVAGIEEVKEEVKEIIEYLKDPVKFQKLGGRPPKGVLLYG
EPGVGKTLLAKAIAGEAHVPFISVSGSDFVGVGAARVRDLFETAKKHAPC
MIFIDEIDAVGRDEREQTLNQLLVEMDGFDTSDGIIVIAATNRPDILDPA
LLRPGRFDRQIFIPKPDVRGRYEILKVHARNKKLAKDVDLEFVARATPGL
TGADLENLLNEAALLAARKGKEEITMEEIEEALDRMTISPKEKEKIAIHE
AGHALMGLVSDDDDKVHKISIIPDKHIYDKKDLYNKILVLLGGRAAEEVF
FGKDGITTGAENDLQRATDLAYRMVSMWGMSDKVGPIAIRAVDTSPDLLR
EIDEEVRRIITEQYEKAKAIVEEYKEPLKAVVKKLLEKETITCEEFVEVF
KLYGIELKDKCK
3D structure
PDB4ww0 The structure of Aquifex aeolicus FtsH in the ADP-bound state reveals a C2-symmetric hexamer.
ChainC
Resolution2.96 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.24.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP C L183 G184 L38 G39
BS02 ZN C H418 H422 D496 H249 H253 D313
BS03 ADP C A158 G198 V199 G200 K201 T202 L203 I334 H338 G362 A363 E366 A13 G53 V54 G55 K56 T57 L58 I174 H178 G202 A203 E206
Gene Ontology
Molecular Function
GO:0004176 ATP-dependent peptidase activity
GO:0004222 metalloendopeptidase activity
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4ww0, PDBe:4ww0, PDBj:4ww0
PDBsum4ww0
PubMed26057670
UniProtO67077|FTSH_AQUAE ATP-dependent zinc metalloprotease FtsH (Gene Name=ftsH)

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