Structure of PDB 4wuz Chain C

Receptor sequence
>4wuzC (length=225) Species: 10710 (Lambdavirus lambda) [Search protein sequence]
TPDIILQRTGIDVRAVEQGDDAWHKLRLGVITASEVHNVIAKPRSGKKWP
DMKMSYFHTLLAEVCTGVAPEVNAKALAWGKQYENDARTLFEFTSGVNVT
ESPIIYRDESMRTACSPDGLCSDGNGLELKCPFTSRDFMKFRLGGFEAIK
SAYMAQVQYSMWVTRKNAWYFANYDPRMKREGLHYVVIERDEKYMASFDE
IVPEFIEKMDEALAEIGFVFGEQWR
3D structure
PDB4wuz Crystal Structure of lambda Exonuclease in Complex with DNA and Ca(2+).
ChainC
Resolution2.38 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) E93 E102 D109 E129 L130 K131
Catalytic site (residue number reindexed from 1) E92 E101 D108 E128 L129 K130
Enzyme Commision number 3.1.11.3: exodeoxyribonuclease (lambda-induced).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C K43 R45 P51 D52 M53 K42 R44 P50 D51 M52
BS02 dna C R45 S46 R44 S45
BS03 PO4 C R28 T33 A34 S35 C116 S117 R27 T32 A33 S34 C115 S116
BS04 CA C D119 E129 D118 E128
Gene Ontology
Molecular Function
GO:0004527 exonuclease activity
GO:0046872 metal ion binding
GO:0051908 double-stranded DNA 5'-3' DNA exonuclease activity
Biological Process
GO:0006259 DNA metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4wuz, PDBe:4wuz, PDBj:4wuz
PDBsum4wuz
PubMed25370446
UniProtP03697|EXO_LAMBD Exonuclease (Gene Name=exo)

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