Structure of PDB 4woq Chain C

Receptor sequence
>4woqC (length=290) Species: 525259 (Clostridioides difficile NAP08) [Search protein sequence]
TDMKGIYSALLVSFDKEGNINEKGLRQIIRHNIDVCKVDGLYVGGSTGEN
FMLSTDEKKRIFEIAKDEVKEEIKLIAQVGSVNLKEAVELAKFTTDLGYD
AISAVTPFYYKFDFEEIKHYYNTIINSVDNRLIIYSIPFLTGVDMSLDQF
GELFENEKIIGVKFTAADFYLLERMRKTFPNKLIFAGFDEMMLPATVLGV
DGAIGSTFNVNGVRARQIFELTKNEKISEALEVQHVTNDLITDILGNGLY
QTIKLLLEEQGVEAGYCRQPMKEATDEMKSRAKEIYRKYF
3D structure
PDB4woq Crystal Structures of CdNal from Clostridium difficile in complex with ketobutyric
ChainC
Resolution2.2 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S58 Y121 Y147 L152 K175 I216
Catalytic site (residue number reindexed from 1) S46 Y109 Y135 L140 K163 I204
Enzyme Commision number 4.1.3.3: N-acetylneuraminate lyase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 2KT C L159 Y182 L147 Y170
Gene Ontology
Molecular Function
GO:0008747 N-acetylneuraminate lyase activity
GO:0016829 lyase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0019262 N-acetylneuraminate catabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:4woq, PDBe:4woq, PDBj:4woq
PDBsum4woq
PubMed
UniProtD5Q364

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