Structure of PDB 4wj7 Chain C

Receptor sequence
>4wj7C (length=129) Species: 9606 (Homo sapiens) [Search protein sequence]
DYIEKEVKYLGQLTSIPGYLNPSSRTEILHFIDNAKRAHQLPGHLTQEHD
AVLSLSAYNVKLAWRDGEDIILRVPIHDIAAVSYVRDDAAHLVVLKTAQE
ACCLVILAAESKVAAEELCCLLGQVFQVV
3D structure
PDB4wj7 Structural Basis for the Disruption of the Cerebral Cavernous Malformations 2 (CCM2) Interaction with Krev Interaction Trapped 1 (KRIT1) by Disease-associated Mutations.
ChainC
Resolution2.753 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C P82 S83 R85 H137 D138 I139 A140 A141 V142 S143 Y144 R146 C210 F217 V219 V220 P22 S23 R25 H77 D78 I79 A80 A81 V82 S83 Y84 R86 C119 F126 V128 V129
External links
PDB RCSB:4wj7, PDBe:4wj7, PDBj:4wj7
PDBsum4wj7
PubMed25525273
UniProtQ9BSQ5|CCM2_HUMAN Cerebral cavernous malformations 2 protein (Gene Name=CCM2)

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