Structure of PDB 4urm Chain C

Receptor sequence
>4urmC (length=191) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
LEAARKRPGMYIGSTSERGLHHLVWEIVDNSIDEALAGYANQIEVVIEKD
NWIKVTDNGRGIPVDIQEKMGRPAVEVILTVLHAGVGSSVVNALSQDLEV
YVHRNETIYHQAYKKGVPQFDLKEVGTTDKTGTVIRFKADGEIFTETTVY
NYETLQQRIRELAFLNKGIQITLRDERDEENVREDSYHYEG
3D structure
PDB4urm Structures of Kibdelomycin Bound to Staphylococcus Aureus Gyrb and Pare Showed a Novel U-Shaped Binding Mode.
ChainC
Resolution2.94 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.6.2.2: DNA topoisomerase (ATP-hydrolyzing).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 XAM C R200 E201 F204 R160 E161 F164
BS02 XAM C N54 E58 D81 G85 I86 P87 I102 H107 G109 T173 N30 E34 D57 G61 I62 P63 I78 H83 G85 T133
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
GO:0005524 ATP binding
Biological Process
GO:0006265 DNA topological change

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Molecular Function
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Biological Process
External links
PDB RCSB:4urm, PDBe:4urm, PDBj:4urm
PDBsum4urm
PubMed24992706
UniProtP0A0K8|GYRB_STAAU DNA gyrase subunit B (Gene Name=gyrB)

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