Structure of PDB 4uoh Chain C

Receptor sequence
>4uohC (length=151) Species: 6689 (Penaeus vannamei) [Search protein sequence]
MVRERTFIAVKPDGVQRGLIGEIIKRFEAKGFKLAGMKYIQASEDLLKQH
YIDLADKPFYPGLCKYMSSGPVVAMCWEGTGVVKTARVMMGETRPADSKP
GTIRGDFCIEVGRNIIHGSDSVESANKEIALWFKPEELVSWTQTNESWIY
E
3D structure
PDB4uoh Structure of Nucleoside Diphosphate Kinase from Pacific Shrimp (Litopenaeus Vannamei) in Binary Complexes with Purine and Pyrimidine Nucleoside Diphosphates
ChainC
Resolution2.007 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K11 Y51 N114 H117 E128
Catalytic site (residue number reindexed from 1) K11 Y51 N114 H117 E128
Enzyme Commision number 2.7.4.6: nucleoside-diphosphate kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP C K11 L54 F59 R87 T93 V111 N114 K11 L54 F59 R87 T93 V111 N114 PDBbind-CN: -logKd/Ki=4.77,Kd=17uM
Gene Ontology
Molecular Function
GO:0004550 nucleoside diphosphate kinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0046872 metal ion binding
Biological Process
GO:0006183 GTP biosynthetic process
GO:0006228 UTP biosynthetic process
GO:0006241 CTP biosynthetic process
GO:0009142 nucleoside triphosphate biosynthetic process
GO:0016310 phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:4uoh, PDBe:4uoh, PDBj:4uoh
PDBsum4uoh
PubMed25195883
UniProtA5J299

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