Structure of PDB 4ubf Chain C

Receptor sequence
>4ubfC (length=322) Species: 9606 (Homo sapiens) [Search protein sequence]
NWEFARMIKEFRATLECHPLTMTDPIEEHRICVCVRKRPLNKQELAKKEI
DVISIPSKCLLLVHEPKLKVDLTKYLENQAFCFDFAFDETASNEVVYRFT
ARPLVQTIFEGGKATCFAYGQTGSGKTHTMGKGIYAMASRDVFLLKNQPC
YRKLGLEVYVTFFEIYNGKLFDLLNKKAKLRVLEDGQQVQVVGLQEHLVN
SADDVIKMIDMGSACRNSSRSHACFQIILRAKGRMHGKFSLVDLAGNEGA
EINKSLLALKECIRALGQNKATPFRESKLTQVLRDSFIGENSRTCMIATI
SPGISSCEYTLNTLRYADRVKE
3D structure
PDB4ubf The C-terminal region of the motor protein MCAK controls its structure and activity through a conformational switch.
ChainC
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG C T355 R456 T127 R216
BS02 ADP C R266 P267 T350 G351 S352 G353 T355 H356 R38 P39 T122 G123 S124 G125 T127 H128
Gene Ontology
Molecular Function
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement

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Molecular Function
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Biological Process
External links
PDB RCSB:4ubf, PDBe:4ubf, PDBj:4ubf
PDBsum4ubf
PubMed25915621
UniProtQ99661|KIF2C_HUMAN Kinesin-like protein KIF2C (Gene Name=KIF2C)

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