Structure of PDB 4u8t Chain C

Receptor sequence
>4u8tC (length=155) Species: 559307 (Zygosaccharomyces rouxii CBS 732) [Search protein sequence]
GAIIPPWIHVPDHSRFFVIKSSSLEHVKKSFYNGIWSSTFYGNKRLSEAY
ESLPQGAKIYLLFSVNASGRFCGVAEMSSNLREDLDTSIWGSRYRHAFKV
RWIVVRDVHNRSLKQFLIPANDMKPVTNSRDTQEIPATISKSILKLFKYV
QSFLD
3D structure
PDB4u8t Molecular basis for the recognition of methylated adenines in RNA by the eukaryotic YTH domain.
ChainC
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna C F204 Y205 F40 Y41 PDBbind-CN: Kd=0.2uM
BS02 rna C K184 S185 S186 H190 W200 S201 T203 Y205 R209 N230 A231 W254 R259 Y260 N276 T293 N294 R296 D297 K20 S21 S22 H26 W36 S37 T39 Y41 R45 N66 A67 W90 R93 Y94 N110 T127 N128 R130 D131 PDBbind-CN: Kd=0.2uM
BS03 rna C R209 R296 R45 R130 PDBbind-CN: Kd=0.2uM
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:4u8t, PDBe:4u8t, PDBj:4u8t
PDBsum4u8t
PubMed25201973
UniProtC5E1V0

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