Structure of PDB 4rav Chain C

Receptor sequence

>4ravC (length=117) Species: 9606 (Homo sapiens) [Search protein sequence]

VQLQESGGGLVQPGGSLRLSCAASGFTFSSYSMSWVRQAPGKGLEWVAVI
SYDGSNKYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARDRY
FDLWGRGTLVTVSSGGG

3D structure

PDB

4rav Structure of a single-chain fv bound to the 17 N-terminal residues of huntingtin provides insights into pathogenic amyloid formation and suppression.

Chain

Resolution

2.5 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	C	S31 S33 S35 W47 V50 I51 S52 Y53 N57 Y59 D99	S30 S32 S34 W46 V49 I50 S51 Y52 N56 Y58 D98

External links

PDB	RCSB:4rav, PDBe:4rav, PDBj:4rav
PDBsum	4rav
PubMed	25861763

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