Structure of PDB 4r9u Chain C

Receptor sequence
>4r9uC (length=248) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
SIVMQLQDVAESTRLGPLSGEVRAGEILHLVGPNGAGKSTLLARMAGMTS
GKGSIQFAGQPLEAWSATKLALHRAYLSQQQTPPFATPVWHYLTLHQHDK
TRTELLNDVAGALALDDKLGRSTNQLSGGEWQRVRLAAVVLQITPQANPA
GQLLLLDQPMCSLDVAQQSALDKILSALSQQGLAIVMSSHDLNHTLRHAH
RAWLLKGGKMLASGRREEVLTPPNLAQAYGMNFRRLDIEGHRMLISTI
3D structure
PDB4r9u Structure of AMP-PNP-bound BtuCD and mechanism of ATP-powered vitamin B12 transport by BtuCD-F.
ChainC
Resolution2.785 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.6.2.8: ABC-type vitamin B12 transporter.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ANP C R15 N35 G36 G38 K39 S40 T41 Q80 R14 N34 G35 G37 K38 S39 T40 Q79
BS02 MG C S40 Q80 S39 Q79
BS03 ANP C R122 Q126 S128 G130 E131 R121 Q125 S127 G129 E130
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0015420 ABC-type vitamin B12 transporter activity
GO:0016887 ATP hydrolysis activity
GO:0042626 ATPase-coupled transmembrane transporter activity
Biological Process
GO:0015889 cobalamin transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0019898 extrinsic component of membrane
GO:0043190 ATP-binding cassette (ABC) transporter complex
GO:1990191 cobalamin transport complex
GO:1990193 BtuCD complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4r9u, PDBe:4r9u, PDBj:4r9u
PDBsum4r9u
PubMed25402482
UniProtP06611|BTUD_ECOLI Vitamin B12 import ATP-binding protein BtuD (Gene Name=btuD)

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