Structure of PDB 4qmg Chain C

Receptor sequence
>4qmgC (length=306) Species: 9606 (Homo sapiens) [Search protein sequence]
PTVQRGIIKMVLSGCAIIVRGQPRGGPPPERQINLSNIRAGNLARRADTP
DEPWAFPAREFLRKKLIGKEVCFTIENKTPQGREYGMIYLGKDTNGENIA
ESLVAEGLATRREGMRANNPEQNRLSECEEQAKAAKKGMWSEGNGSHTIR
DLKYTIENPRHFVDSHHQKPVNAIIEHVRDGSVVRALLLPDYYLVTVMLS
GIKCPTFRREAETPEPFAAEAKFFTESRLLQRDVQIILESCHNQNILGTI
LHPNGNITELLLKEGFARCVDWSIAVYTRGAEKLRAAERFAKERRLRIWR
DYVAPT
3D structure
PDB4qmg Structural Insights into the Tumor-Promoting Function of the MTDH-SND1 Complex.
ChainC
Resolution2.701 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.31.1: micrococcal nuclease.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C M222 N270 M198 N243
BS02 peptide C P39 G42 P43 R87 K88 K93 F244 E247 F250 F251 S254 R255 R259 D260 H279 N281 R324 P23 G26 P27 R63 K64 K69 F217 E220 F223 F224 S227 R228 R232 D233 H252 N254 R297
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004518 nuclease activity

View graph for
Molecular Function
External links
PDB RCSB:4qmg, PDBe:4qmg, PDBj:4qmg
PDBsum4qmg
PubMed25242325
UniProtQ7KZF4|SND1_HUMAN Staphylococcal nuclease domain-containing protein 1 (Gene Name=SND1)

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