Structure of PDB 4qf9 Chain C

Receptor sequence
>4qf9C (length=244) Species: 10116 (Rattus norvegicus) [Search protein sequence]
TLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFLYDVK
LVPDGKYGAQNDKGEWNGMVKELIDHRADLAVAPLTITYVREKVIDFSKP
FMTLGISILYRKGTPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTY
EKMWAFMSSSALVKNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQI
GGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKLHMMKEKWW
3D structure
PDB4qf9 Binding Mode of an alpha-Amino Acid-Linked Quinoxaline-2,3-dione Analogue at Glutamate Receptor Subtype GluK1.
ChainC
Resolution2.28 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 35K C E13 Y16 Y61 P88 T90 R95 T192 Y216 E9 Y12 Y57 P84 T86 R91 T185 Y209 MOAD: Ki=37.1uM
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:4qf9, PDBe:4qf9, PDBj:4qf9
PDBsum4qf9
PubMed25856736
UniProtP22756|GRIK1_RAT Glutamate receptor ionotropic, kainate 1 (Gene Name=Grik1)

[Back to BioLiP]