Structure of PDB 4qbr Chain C

Receptor sequence
>4qbrC (length=136) Species: 9606 (Homo sapiens) [Search protein sequence]
SRERLVYEVRQKCRNIEDICISCGSLNVTLEHPLFVGGMCQNCKNCFLEC
AYQYDDDGYQSYCTICCGGREVLMCDNNNCCRCFCVECVDLLVGPGAAQA
AIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFFA
3D structure
PDB4qbr Engineering of a histone-recognition domain in a de novo DNA methyltransferase alters the epigenetic landscape of ESCs
ChainC
Resolution1.902 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.-
2.1.1.37: DNA (cytosine-5-)-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C D529 D531 Y533 Q534 G543 R544 E545 V546 L547 M548 D550 A575 I576 E578 W581 D55 D57 Y59 Q60 G69 R70 E71 V72 L73 M74 D76 A101 I102 E104 W107
BS02 ZN C C549 C554 C583 C586 C75 C80 C109 C112
BS03 ZN C C537 C540 C559 C562 C63 C66 C85 C88
BS04 ZN C C494 C497 C517 C20 C23 C43
External links
PDB RCSB:4qbr, PDBe:4qbr, PDBj:4qbr
PDBsum4qbr
PubMed
UniProtQ9Y6K1|DNM3A_HUMAN DNA (cytosine-5)-methyltransferase 3A (Gene Name=DNMT3A)

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