Structure of PDB 4pxi Chain C

Receptor sequence
>4pxiC (length=200) Species: 1902 (Streptomyces coelicolor) [Search protein sequence]
LRAEQTRATIIGAAADLFDRRGYESTTLSEIVAHAGVTKGALYFHFAAKE
DLAHAILEIQSRTSRRLAKDLDGRGYSSLEALMRLTFGMARLCVQGPVLR
AGLRLATAGVVRPPLPHPFTEWREIATSRLLDAVRQSDVHQDIDVDSVAH
TLVCSVVGTRVVGREPRRLAEMWYILIRGMVPVTRRARYVTLAARLEQET
3D structure
PDB4pxi Structural and functional basis of transcriptional regulation by TetR family protein CprB from S. coelicolor A3(2)
ChainC
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C L5 R6 A7 T10 T42 K43 G44 A45 F48 H49 L1 R2 A3 T6 T38 K39 G40 A41 F44 H45 PDBbind-CN: Kd=200nM
BS02 dna C L5 R6 T31 L32 Y47 A52 K53 L1 R2 T27 L28 Y43 A48 K49 PDBbind-CN: Kd=200nM
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:4pxi, PDBe:4pxi, PDBj:4pxi
PDBsum4pxi
PubMed25092919
UniProtO66122

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