Structure of PDB 4pgh Chain C

Receptor sequence
>4pghC (length=353) Species: 4558 (Sorghum bicolor) [Search protein sequence]
AVADEEACMYAMQLASSSILPMTLKNALELGLLEVLQKDAGKALAAEEVV
ARLPVAPTNPAAADMVDRMLRLLASYDVVKCQMEDKDGKYERRYSAAPVG
KWLTPNEDGVSMAALALMNQDKVLMESWYYLKDAVLDGGIPFNKAYGMTA
FEYHGTDPRFNRVFNEGMKNHSVIITKKLLEFYTGFDESVSTLVDVGGGI
GATLHAITSHHSHIRGVNFDLPHVISEAPPFPGVQHVGGDMFKSVPAGDA
ILMKWILHDWSDAHCATLLKNCYDALPEKGGKVIVVECVLPVTTDAVPKA
QGVFHVDMIMLAHNPGGRERYEREFRDLAKAAGFSGFKATYIYANAWAIE
FIK
3D structure
PDB4pgh Determination of the Structure and Catalytic Mechanism of Sorghum bicolor Caffeic Acid O-Methyltransferase and the Structural Impact of Three brown midrib12 Mutations.
ChainC
Resolution2.8 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H267 D268 E296 E328
Catalytic site (residue number reindexed from 1) H258 D259 E287 E319
Enzyme Commision number 2.1.1.68: caffeate O-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAM C G206 D229 L230 D249 M250 F251 K263 G197 D220 L221 D240 M241 F242 K254
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0008171 O-methyltransferase activity
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
GO:0017096 acetylserotonin O-methyltransferase activity
GO:0030755 quercetin 3-O-methyltransferase activity
GO:0033799 myricetin 3'-O-methyltransferase activity
GO:0046983 protein dimerization activity
GO:0047763 caffeate O-methyltransferase activity
Biological Process
GO:0006970 response to osmotic stress
GO:0007623 circadian rhythm
GO:0009058 biosynthetic process
GO:0009809 lignin biosynthetic process
GO:0010344 seed oilbody biogenesis
GO:0010555 response to mannitol
GO:0030187 melatonin biosynthetic process
GO:0031537 regulation of anthocyanin metabolic process
GO:0032259 methylation
GO:0042428 serotonin metabolic process
GO:0048354 mucilage biosynthetic process involved in seed coat development
GO:0051555 flavonol biosynthetic process
GO:0090333 regulation of stomatal closure
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4pgh, PDBe:4pgh, PDBj:4pgh
PDBsum4pgh
PubMed24948836
UniProtC5YH12

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