Structure of PDB 4pfp Chain C

Receptor sequence
>4pfpC (length=766) Species: 9823 (Sus scrofa) [Search protein sequence]
KPVWAPHPTDGFQVGNIVDIGPDSLTIEPLNQKGKTFLALINQVFPAEED
SKKDVEDNCSLMYLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIP
KIYSSETIKSYQGKSLGTMPPHVFAIADKAFRDMKVLKLSQSIIVSGESG
AGKTENTKFVLRYLTESYGTGQDIDDRIVEANPLLEAFGNAKTVRNNNSS
RFGKFVEIHFNEKSSVVGGFVSHYLLEKSRICVQGKEERNYHIFYRLCAG
ASEDIRERLHLSSPDNFRYLNRGCTRYFANKETDKQILQNRKSPEYLKAG
SLKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNIDFEE
AGSTSGGCNLKNKSTQALEYCAELLGLDQDDLRVSLTTRVMLTGTVIKVP
LKVEQANNARDALAKTVYSHLFDHVVNRVNQCFPFETSSYFIGVLDIAGF
EYFEHNSFEQFCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHYVD
NQDCIDLIEARLVGILDILDEENRLPQPSDQHFTSAVHQKHKDHFRLSIP
RKSKLAIHRNIRDDEGFIIRHFAGAVCYETTQFVEKNNDALHMSLESLIC
ESRDKFIRELFEGKLSFISVGNKFKTQLNLLLDKLRSTGASFIRCIKPNL
KMTSHHFEGAQILSQLQCSGMVSVLDLMQGGFPSRASFHELYNMYKKYMP
DKLARLDPRLFCKALFKALGLNEIDYKFGLTKVFFRPGKFAEFDQIMKSD
PDHLAELVKRVNHWLI
3D structure
PDB4pfp How actin initiates the motor activity of Myosin.
ChainC
Resolution2.32 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S153 T158 S203 S204 G459 E461
Catalytic site (residue number reindexed from 1) S149 T154 S199 S200 G449 E451
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP C N98 P99 Y100 S153 G154 G156 K157 T158 E159 N200 N94 P95 Y96 S149 G150 G152 K153 T154 E155 N196
BS02 PO4 C S153 K157 S203 S204 A458 G459 S149 K153 S199 S200 A448 G449
BS03 MG C T158 S204 T154 S200
Gene Ontology
Molecular Function
GO:0003774 cytoskeletal motor activity
GO:0005524 ATP binding
GO:0051015 actin filament binding
Cellular Component
GO:0016459 myosin complex

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Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:4pfp, PDBe:4pfp, PDBj:4pfp
PDBsum4pfp
PubMed25936506
UniProtF1RQI7

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