Structure of PDB 4ozg Chain C

Receptor sequence
>4ozgC (length=180) Species: 9606 (Homo sapiens) [Search protein sequence]
IVADHVASYGVNLYQSYGPSGQYTHEFDGDEQFYVDLGRKETVWCLPVLR
QFRFDPQFALTNIAVLKHNLNSLIKRSNSTAATNEVPEVTVFSKSPVTLG
QPNILICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISY
LTLLPSAEESYDCKVEHWGLDKPLLKHWEP
3D structure
PDB4ozg T-cell receptor recognition of HLA-DQ2-gliadin complexes associated with celiac disease.
ChainC
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide C Y9 R52 F54 F58 N62 V65 H68 N69 N71 L73 R76 Y9 R53 F54 F58 N62 V65 H68 N69 N71 L73 R76
BS02 CA C E85 N111 E85 N111
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:4ozg, PDBe:4ozg, PDBj:4ozg
PDBsum4ozg
PubMed24777060
UniProtP01909|DQA1_HUMAN HLA class II histocompatibility antigen, DQ alpha 1 chain (Gene Name=HLA-DQA1)

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