Structure of PDB 4oqd Chain C

Receptor sequence
>4oqdC (length=241) Species: 1906 (Streptomyces fradiae) [Search protein sequence]
GPQADYSGEIAELYDLVHQGKGKDYHREAADLAALVRRHSPKAASLLDVA
CGTGMHLRHLADSFGTVEGLELSADMLAIARRRNPDAVLHHGDMRDFSLG
RRFSAVTCMFSSIGHLAGQAELDAALERFAAHVLPDGVVVVEPWWFPENF
TPGYVAAGTVEAGGTTVTRVSHSSREGEATRIEVHYLVAGPDRGITHHEE
SHRITLFTREQYERAFTAAGLSVEFMPGGPSGRGLFTGLPG
3D structure
PDB4oqd Production of a novel N-monomethylated dideoxysugar.
ChainC
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.235: dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH C Y14 Y22 Y33 A58 G60 E79 L80 M84 D101 M102 F118 S120 H123 Y6 Y14 Y25 A50 G52 E71 L72 M76 D93 M94 F110 S112 H115
BS02 QDM C Y14 K29 F118 S119 W152 W153 F158 T159 Y162 R177 S179 S181 R241 Y6 K21 F110 S111 W144 W145 F150 T151 Y154 R169 S171 S173 R233
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
GO:0042803 protein homodimerization activity
Biological Process
GO:0009058 biosynthetic process
GO:0017000 antibiotic biosynthetic process
GO:0032259 methylation

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Molecular Function
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Biological Process
External links
PDB RCSB:4oqd, PDBe:4oqd, PDBj:4oqd
PDBsum4oqd
PubMed24512254
UniProtP95748|TYLM1_STRFR dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase (Gene Name=tylM1)

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