Structure of PDB 4ofm Chain C

Receptor sequence
>4ofmC (length=206) Species: 51031 (Necator americanus) [Search protein sequence]
MVHYKLTYFAIRGAGECARQIFALADQEFEDVRLDKEQFAKVKPDLPFGQ
VPVLEVDGKQLAQSLAICRYLARQFGFAGKSTFDEAVVDSLADQYSDYRV
EIKSFFYTVIGMREGDVEQLKKEVLLPARDKFFGFITKFLKKSPSGFLVG
DSLTWVDLLVSEHNATMLTFVPEFLEGYPEVKEHMEKIRAIPKLKKWIET
RPETLF
3D structure
PDB4ofm Structure of glutathione S-transferase 1 from the major human hookworm parasite Necator americanus (Na-GST-1) in complex with glutathione.
ChainC
Resolution2.64 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y8 A14 R19 V109
Catalytic site (residue number reindexed from 1) Y8 A14 R19 V109
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GSH C F9 F39 Q50 V51 Q63 S64 F9 F39 Q50 V51 Q63 S64
Gene Ontology
Molecular Function
GO:0004364 glutathione transferase activity
GO:0016740 transferase activity
Biological Process
GO:0006749 glutathione metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4ofm, PDBe:4ofm, PDBj:4ofm
PDBsum4ofm
PubMed25195885
UniProtD3U1A5

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