Structure of PDB 4nxu Chain C

Receptor sequence
>4nxuC (length=332) Species: 9606 (Homo sapiens) [Search protein sequence]
LRMSLQEKLLTYYRNRAAIPAGEQARAKQAAVDICAELRSFLRAKLPDMP
LRDMYLSGSLYDDLQVVTADHIQLIVPLVLEQNLWSCIPGEDTIMNVPGF
FLVRRENPEYFPRGSSYWDRCVVGGYLSPKTVADTFEKVVAGSINWPAIG
SLLDYVIRPAPPPEALTLEVQYERDKHLFIDFLPSVTLGDTVLVAKPHRL
AQYDNLWRLSLRPAETARLRALDQADSGCRSLCLKILKAICKSTPALGHL
TASQLTNVILHLAQEEADWSPDMLADRFLQALRGLISYLEAGVLPSALNP
KVNLFAELTPEEIDELGYTLYCSLSEPEVLLQ
3D structure
PDB4nxu Structural and functional analysis of MiD51, a dynamin receptor required for mitochondrial fission.
ChainC
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ADP C S187 S189 H201 Q203 V324 K326 S340 R342 K368 A382 S57 S59 H71 Q73 V194 K196 S210 R212 K238 A252 MOAD: Kd=2.9uM
Gene Ontology
Biological Process
GO:0007005 mitochondrion organization
Cellular Component
GO:0005741 mitochondrial outer membrane

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:4nxu, PDBe:4nxu, PDBj:4nxu
PDBsum4nxu
PubMed24515348
UniProtQ9NQG6|MID51_HUMAN Mitochondrial dynamics protein MIEF1 (Gene Name=MIEF1)

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