Structure of PDB 4nhd Chain C

Receptor sequence
>4nhdC (length=317) Species: 243277 (Vibrio cholerae O1 biovar El Tor str. N16961) [Search protein sequence]
AMYSKILGTGSYLPSQVRTNADLEKMVETSDEWIVARTGIRERRIAADNE
TVADMAFFAAQNAINMAGIDKHDIDMIIVATTSASHTFPSAACQVQGKLG
IKGCPAFDLAAACSGFMYALSIADQHVKSGMCKHVLVIGADALSKTCDPT
DRSTIILFGDGAGAVVVGASNEPGILSTHIHADGEFGDLLSLEVPVRGGD
SDKWLHMAGNEVFKVAVTQLSKLVVDTLKANNMHKSELDWLVPHQANYRI
ISATAKKLSMSLDQVVITLDRHGNTSAATVPTALDEAVRDGRIQRGQMLL
LEAFGGGFTWGSALVKF
3D structure
PDB4nhd Crystal structure of beta-ketoacyl-ACP synthase III (FabH) from Vibrio Cholerae in complex with Coenzyme A
ChainC
Resolution1.78 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.180: beta-ketoacyl-[acyl-carrier-protein] synthase III.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 COA C T28 W32 R36 R151 I155 G208 N209 F212 A245 N246 R248 F303 T29 W33 R37 R152 I156 G209 N210 F213 A246 N247 R249 F304
BS02 CA C D72 D74 D73 D75
BS03 CA C N48 D53 N49 D54
Gene Ontology
Molecular Function
GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity
GO:0016746 acyltransferase activity
GO:0033818 beta-ketoacyl-acyl-carrier-protein synthase III activity
Biological Process
GO:0006633 fatty acid biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4nhd, PDBe:4nhd, PDBj:4nhd
PDBsum4nhd
PubMed
UniProtQ9KQH5|FABH1_VIBCH Beta-ketoacyl-[acyl-carrier-protein] synthase III 1 (Gene Name=fabH1)

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