Structure of PDB 4ng2 Chain C

Receptor sequence
>4ng2C (length=166) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
ALVDGFLELERSSGKLEWSAILQKMASDLGFSKILFGLLPKDSQDYENAF
IVGNYPAAWREHYDRAGYARVDPTVSHCTQSVLPIFWEPSIYQTRKQHEF
FEEASAAGLVYGLTMPLHGARGELGALSLSVEAENRAEANRFMESVLPTL
WMLKDYALQSGAGLAF
3D structure
PDB4ng2 QsIA disrupts LasR dimerization in antiactivation of bacterial quorum sensing
ChainC
Resolution2.413 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 OHN C L36 I52 Y56 W60 D73 T75 W88 L110 L125 G126 S129 L35 I51 Y55 W59 D72 T74 W87 L109 L124 G125 S128 BindingDB: EC50=139nM
External links
PDB RCSB:4ng2, PDBe:4ng2, PDBj:4ng2
PDBsum4ng2
PubMed24319092
UniProtP25084|LASR_PSEAE Transcriptional activator protein LasR (Gene Name=lasR)

[Back to BioLiP]