Structure of PDB 4mz8 Chain C

Receptor sequence
>4mz8C (length=349) Species: 192222 (Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819) [Search protein sequence]
KRALTFEDVLLRPGYSEVLPKEVKIHTKLTKNITLNMPLISAAMDTVTEH
RAAIMMARLGGLGVIHKNMDIASQVREVKRVKKSESEYPDANKDNFGRLR
VGAAIGVGQMDRVDALVEAGVDVVVLDSAHGHSKGIIDTVKAIKAKYPNL
DLIAGNIATAAAAKALCEAGVDAVKVGIGPGSICTTRIVSGVGVPQISAI
DECVEEANKFGVPVIADGGIKYSGDIAKALAVGASSVMIGSLLAGTDESP
GELFTYQGRQYKSYRGMGSLGAMQLVPEGIEGRVPYVGSIRSVVHQLLGG
LRSSMGYVGAKDIEDFQKRAEFVEITTAGLKESHVHDVTITHEAPNYKV
3D structure
PDB4mz8 Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase, with a Internal Deletion of CBS Domain from Campylobacter jejuni complexed with inhibitor compound C91
ChainC
Resolution2.5004 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.205: IMP dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IMP C M48 G298 S299 I300 C301 D334 Y381 G383 M384 G385 E411 G412 M44 G181 S182 I183 C184 D217 Y264 G266 M267 G268 E278 G279
BS02 C91 C A246 H247 M390 E411 A129 H130 M273 E278
BS03 C91 C G439 Y440 G306 Y307
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0003938 IMP dehydrogenase activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0006164 purine nucleotide biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4mz8, PDBe:4mz8, PDBj:4mz8
PDBsum4mz8
PubMed
UniProtQ0P9J4

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