Structure of PDB 4mz1 Chain C

Receptor sequence
>4mz1C (length=361) Species: 192222 (Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819) [Search protein sequence]
MKIVKRALTFEDVLLRPGYSEVLPKEVKIHTKLTKNITLNMPLISAAMDT
VTEHRAAIMMARLGGLGVIHKNMDIASQVREVKRVKKSESGGIKKRKEYP
DANKDNFGRLRVGAAIGVGQMDRVDALVEAGVDVVVLDSAHGHSKGIIDT
VKAIKAKYPNLDLIAGNIATAAAAKALCEAGVDAVKVGIGPGSICTTRIV
SGVGVPQISAIDECVEEANKFGVPVIADGGIKYSGDIAKALAVGASSVMI
GSLLAGTDESPGELFTYQGRQYKSYRGMGSLGAMQKLVPEGIEGRVPYVG
SIRSVVHQLLGGLRSSMGYVGAKDIEDFQKRAEFVEITTAGLKESHVHDV
TITHEAPNYKV
3D structure
PDB4mz1 Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase, with a Internal Deletion of CBS Domain from Campylobacter jejuni complexed with inhibitor compound P12
ChainC
Resolution2.3991 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.205: IMP dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IMP C M48 G298 S299 I300 C301 D334 G357 S358 Y381 G383 M384 G385 E411 M48 G192 S193 I194 C195 D228 G251 S252 Y275 G277 M278 G279 E290
BS02 2F1 C A246 H247 M384 G385 E411 A140 H141 M278 G279 E290
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0003938 IMP dehydrogenase activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0006164 purine nucleotide biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4mz1, PDBe:4mz1, PDBj:4mz1
PDBsum4mz1
PubMed
UniProtQ0P9J4

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