Structure of PDB 4mvn Chain C

Receptor sequence
>4mvnC (length=196) Species: 93061 (Staphylococcus aureus subsp. aureus NCTC 8325) [Search protein sequence]
EKNVKEITDATKEPYNSVVAFVGGTGVVVGKNTIVTNKHIAKSNDIFKNR
VSAHHSSGGNYDVKDIVEYPGKEDLAIVHVHETSTEGLNFNKNVSYTKFA
DGAKVKDRISVIGYPKGAQTKYKMFESTGTINHISGTFMEFDAYAQPGNS
GSPVLNSKHELIGILYAGSGKDESEKNFGVYFTPQLKEFIQNNIEK
3D structure
PDB4mvn Development and binding characteristics of phosphonate inhibitors of SplA protease from Staphylococcus aureus.
ChainC
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 I1S C Q150 P151 S154 A171 G172 G174 Q146 P147 S150 A167 G168 G170
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4mvn, PDBe:4mvn, PDBj:4mvn
PDBsum4mvn
PubMed24375505
UniProtQ2FXC2|SPLA_STAA8 Serine protease SplA (Gene Name=splA)

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