Structure of PDB 4mll Chain C

Receptor sequence
>4mllC (length=251) Species: 562 (Escherichia coli) [Search protein sequence]
STDISTVASPLFEGTEGCFLLYDASTNAEIAQFNKAKCATQMAPDSTFDI
ALSLMAFDAEIIDQKTIFKWDKTPKGMEIWNSNHTPKTWMQFSVVWVSQE
ITQKIGLNKIKNYLKDFDYGNQDFSGDKERNNGLTEAWLESSLKISPEEQ
IQFLRKIINHNLPVKNSAIENTIENMYLQDLDNSTKLYGKTGAGFTANRT
LQNGWFEGFIISKSGHKYVFVSALTGNLGSNLTSSIKAKKNAITILNTLN
L
3D structure
PDB4mll Structural Origins of Oxacillinase Specificity in Class D beta-Lactamases.
ChainC
Resolution1.37 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S67 D70 S115 S120 W160 A215
Catalytic site (residue number reindexed from 1) S46 D49 S93 S98 W138 A193
Enzyme Commision number 3.5.2.6: beta-lactamase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 1S6 C S67 W102 T213 G214 A215 L255 S258 S46 W80 T191 G192 A193 L232 S235
BS02 1S6 C K236 S237 G238 K213 S214 G215
Gene Ontology
Molecular Function
GO:0008658 penicillin binding
GO:0008800 beta-lactamase activity
GO:0016787 hydrolase activity
Biological Process
GO:0046677 response to antibiotic

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Molecular Function
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Biological Process
External links
PDB RCSB:4mll, PDBe:4mll, PDBj:4mll
PDBsum4mll
PubMed24165180
UniProtP13661|BLO1_ECOLX Beta-lactamase OXA-1 (Gene Name=bla)

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