Structure of PDB 4mky Chain C

Receptor sequence
>4mkyC (length=284) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
QRVTLTNADKVLYPATGTTKSDIFDYYAGVAEVMLGHIAGRPATRKRWPN
GVDQPAFFEKQLALSAPPWLSRATVAHRSGTTTYPIIDSATGLAWIAQQA
ALEVHVPQWRFVAEPGSGELNPGPATRLVFDLDPGEGVMMAQLAEVARAV
RDLLADIGLVTFPVTSGSKGLHLYTPLDEPVSSRGATVLAKRVAQRLEQA
MPALVTSTMTKSLRAGKVFVDWSQNSGSKTTIAPYSLRGRTHPTVAAPRT
WAELDDPALRQLSYDEVLTRIARDGDLLERLDAD
3D structure
PDB4mky Molecular Basis for DNA Double-Strand Break Annealing and Primer Extension by an NHEJ DNA Polymerase.
ChainC
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.5.1.1: DNA ligase (ATP).
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna C K19 K29 R56 P58 F66 S74 K10 K20 R47 P49 F57 S65
BS02 dna C F66 F67 K69 H86 R87 F57 F58 K60 H77 R78
BS03 dna C K220 R223 D230 K211 R214 D221
External links
PDB RCSB:4mky, PDBe:4mky, PDBj:4mky
PDBsum4mky
PubMed24239356
UniProtP9WNV3|LIGD_MYCTU Multifunctional non-homologous end joining DNA repair protein LigD (Gene Name=ligD)

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