Structure of PDB 4mit Chain C

Receptor sequence
>4mitC (length=181) Species: 885315 (Entamoeba histolytica HM-3:IMSS) [Search protein sequence]
EKPTSIKLVVVGDGAVGKTCLLISYSIRKFPEDYIPTVFDNYVVSLTAGT
RQIQLALWDTAGLEEYDQLRPLSYSSASIFLICFSVTSSVSYDNVITKWH
PEVIHFAPKVPIILVGTKLDTRNDPAIVKRLTEQGMTVINTAKGEELKNR
IKAVKYIECSAKTSENLKTVFDEAVKTVLMN
3D structure
PDB4mit Entamoeba histolytica RacC Selectively Engages p21-Activated Kinase Effectors.
ChainC
Resolution2.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GTP C G19 A20 G22 K23 T24 C25 F35 E37 Y39 T42 G67 K123 D125 S165 A166 K167 G14 A15 G17 K18 T19 C20 F30 E32 Y34 T37 G62 K118 D120 S160 A161 K162
BS02 MG C T24 T42 T19 T37
BS03 MG C A112 P113 K114 A107 P108 K109
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0007264 small GTPase-mediated signal transduction
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4mit, PDBe:4mit, PDBj:4mit
PDBsum4mit
PubMed25529118
UniProtQ24816|RACC_ENTH1 Rho-related protein racC (Gene Name=RACC)

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