Structure of PDB 4ma8 Chain C

Receptor sequence
>4ma8C (length=108) Species: 10090 (Mus musculus) [Search protein sequence]
GAVVGGLGGYMLGSAMSRPMIHFGNDWEDRYYRENMYRYPNQVYYRPVDQ
YSNQNNFVHDCVNITIKQHTVTTTTKGENFTETDVKMMERVVEQMCVTQY
QKESQAYY
3D structure
PDB4ma8 Structural basis of prion inhibition by phenothiazine compounds.
ChainC
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 Z80 C L125 G126 I182 K185 Q186 L7 G8 I64 K67 Q68 BindingDB: EC50=2000nM
Gene Ontology
Biological Process
GO:0051260 protein homooligomerization
Cellular Component
GO:0016020 membrane

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Biological Process
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Cellular Component
External links
PDB RCSB:4ma8, PDBe:4ma8, PDBj:4ma8
PDBsum4ma8
PubMed24373770
UniProtP04925|PRIO_MOUSE Major prion protein (Gene Name=Prnp)

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