Structure of PDB 4lmg Chain C

Receptor sequence
>4lmgC (length=121) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
LIHLDPVPSFEDRHEIKPWLQKIFYPQGIDIVIERSDSSKVTFKCRSVAC
PFRIRAAYSVRLQKWNVVVMNNIHSHELRFDLITKTDDYKKFKENLRQKN
DEKAIKTFDELEYKASLNLPL
3D structure
PDB4lmg Molecular mechanism and structure of the Saccharomyces cerevisiae iron regulator Aft2.
ChainC
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C R76 S80 K81 Y117 V119 R35 S39 K40 Y58 V60
BS02 dna C R54 K58 V73 I74 E75 R76 S77 S88 R13 K17 V32 I33 E34 R35 S36 S47
BS03 dna C E161 K165 E102 K106
BS04 ZN C C86 C109 H133 H135 C45 C50 H74 H76
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
Biological Process
GO:0010106 cellular response to iron ion starvation
GO:0045944 positive regulation of transcription by RNA polymerase II

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Molecular Function
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Biological Process
External links
PDB RCSB:4lmg, PDBe:4lmg, PDBj:4lmg
PDBsum4lmg
PubMed24591629
UniProtQ08957|AFT2_YEAST Iron-regulated transcriptional activator AFT2 (Gene Name=AFT2)

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