Structure of PDB 4ljq Chain C

Receptor sequence
>4ljqC (length=192) Species: 9606 (Homo sapiens) [Search protein sequence]
QGLAMYLQEGIDCPKCKFSYALGCMHFHCTQCRHQFCSGCYNAFYAKNKC
PEPNCRVKKSLHGHHPRDCLFYLRDWTALRLQKLLQDNNVMFNTEPPGGC
RVIEDEACGKETPAGYAGLCQAHYKEYLVSLINAHSLDPATLYEVEELET
ATERYLHVRPQPLAGEDPPAYQARLLQKLTEEVPLGQSIPRR
3D structure
PDB4ljq Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP.
ChainC
Resolution2.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.31: RBR-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN C H887 H889 H26 H28
BS02 ZN C C871 C874 C890 C893 C13 C16 C29 C32
BS03 ZN C C898 C901 H926 C930 C37 C40 H65 C69
BS04 ZN C C911 C916 H923 H925 C50 C55 H62 H64
BS05 ZN C C969 C986 C998 H1001 C100 C108 C120 H123
Gene Ontology
Molecular Function
GO:0004842 ubiquitin-protein transferase activity
GO:0008270 zinc ion binding
Cellular Component
GO:0071797 LUBAC complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:4ljq, PDBe:4ljq, PDBj:4ljq
PDBsum4ljq
PubMed24141947
UniProtQ96EP0|RNF31_HUMAN E3 ubiquitin-protein ligase RNF31 (Gene Name=RNF31)

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