Structure of PDB 4lcc Chain C

Receptor sequence
>4lccC (length=341) Species: 9913 (Bos taurus) [Search protein sequence]
IQRPPKIQVYSRHPPNYLNCYVYGFHPPQIEIDLLKIKSEQSDLSFSKDW
SFYLLSHATPNSKDQYSCRVKHVTLEQPRIVKWDRTHSLRYFRLGISEIP
EFISAGYVDSHPITMYNSVSQLKEPRALWMEENLAPDHWERYTQLLRGWQ
QMFKVELKQLQHHYNHSGFHTYQRMIGCELLEDGSITGFLQYAYDGQDFL
IFNKDTLSWMAMDNVADIIRRVWEANQHELLYQKNWLEEECIAWLKRFLE
YGKDALQRTEPPKVRVNHKTTLYCRAYGFYPPEISINWMKNGEEIFQDTD
YGGILPSGDGTYQTWVSVELGDIYSCHVEHGGVHMVLQGFQ
3D structure
PDB4lcc MAIT Recognition of a Stimulatory Bacterial Antigen Bound to MR1.
ChainC
Resolution3.263 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 1XL C Y120 R122 K156 Y175 W182 R207 Y265 Y91 R93 K123 Y142 W149 R174 Y232
Gene Ontology
Molecular Function
GO:0023026 MHC class II protein complex binding
GO:0042605 peptide antigen binding
Biological Process
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I
GO:0002503 peptide antigen assembly with MHC class II protein complex
GO:0006955 immune response
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0050778 positive regulation of immune response
GO:0050870 positive regulation of T cell activation
Cellular Component
GO:0005576 extracellular region
GO:0005765 lysosomal membrane
GO:0031902 late endosome membrane
GO:0042612 MHC class I protein complex
GO:0042613 MHC class II protein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4lcc, PDBe:4lcc, PDBj:4lcc
PDBsum4lcc
PubMed24108697
UniProtC1ITJ8;
P01888

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