Structure of PDB 4k6f Chain C

Receptor sequence
>4k6fC (length=245) Species: 216591 (Burkholderia cenocepacia J2315) [Search protein sequence]
KRIAVVTGGMGGLGEAVSIRLNDAGHRVVVTYSPNNTGADRWLTEMHAAG
REFHAYPVDVADHDSCQQCIEKIVRDVGPVDILVNNAGITRDMTLRKLDK
VNWDAVIRTNLDSVFNMTKPVCDGMVERGWGRIVNISSVNGSKGSVGQTN
YAAAKAGMHGFTKSLALEIARKGVTVNTVSPGYLATKMVTAIPQDILDTK
ILPQIPAGRLGKPEEVAALVAYLCSEEAGFVTGSNIAINGGQHMH
3D structure
PDB4k6f X-ray crystal structure of a putative Acetoacetyl-CoA reductase from Burkholderia cenocepacia bound to the co-factor NADP
ChainC
Resolution1.5 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) G14 N104 S140 Y153 K157
Catalytic site (residue number reindexed from 1) G12 N102 S138 Y151 K155
Enzyme Commision number 1.1.1.36: acetoacetyl-CoA reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP C G10 G13 G14 L15 Y34 S35 N38 V60 D61 V62 N88 A89 G90 I91 Y153 K157 P183 L186 G8 G11 G12 L13 Y32 S33 N36 V58 D59 V60 N86 A87 G88 I89 Y151 K155 P181 L184
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016491 oxidoreductase activity
GO:0018454 acetoacetyl-CoA reductase activity
Biological Process
GO:0042619 poly-hydroxybutyrate biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4k6f, PDBe:4k6f, PDBj:4k6f
PDBsum4k6f
PubMed
UniProtB4EAU4

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