Structure of PDB 4isr Chain C

Receptor sequence
>4isrC (length=413) Species: 1491 (Clostridium botulinum) [Search protein sequence]
INDSKILSLQNKKNTLMDTSGYNAEVRVEGNVQLNPIFPFDFKLGSSGDD
RGKVIVTQNENIVYNAMYESFSISFWIRINKWVSNLPGYTIIDSVKNNSG
WSIGIISNFLVFTLKQNENSEQDINFSYDISKNAAGYNKWFFVTITTNMM
GNMMIYINGKLIDTIKVKELTGINFSKTITFQMNKIPNDNINMWIRDFYI
FAKELDDKDINILFNSLQYTNVVKDYWGNDLRYDKEYYMINVNYMNRYMS
KKGNGIVFNTRKNNNDFNEGYKIIIKRIRGNTNDTRVRGENVLYFNTTID
NKQYSLGMYKPSRNLGTDLVPLGALDQPMDEIRKYGSFIIQPCNTFDYYA
SQLFLSSNATTNRLGILSIGSYSFKLGDDYWFNHEYLIPVIKIEHYASLL
ESTSTHWVFVPAS
3D structure
PDB4isr Crystal Structures of Botulinum Neurotoxin DC in Complex with Its Protein Receptors Synaptotagmin I and II.
ChainC
Resolution2.59 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K906 I969
Catalytic site (residue number reindexed from 1) K43 I106
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C M1179 Y1180 K1181 P1182 N1185 L1190 V1191 Y1206 L1235 E1265 M308 Y309 K310 P311 N314 L319 V320 Y335 L364 E394
Gene Ontology
Cellular Component
GO:0005576 extracellular region

View graph for
Cellular Component
External links
PDB RCSB:4isr, PDBe:4isr, PDBj:4isr
PDBsum4isr
PubMed23932591
UniProtQ9LBR1

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