Structure of PDB 4isq Chain C

Receptor sequence
>4isqC (length=414) Species: 1491 (Clostridium botulinum) [Search protein sequence]
SINDSKILSLQNKKNTLMDTSGYNAEVRVEGNVQLNPIFPFDFKLGSSGD
DRGKVIVTQNENIVYNAMYESFSISFWIRINKWVSNLPGYTIIDSVKNNS
GWSIGIISNFLVFTLKQNENSEQDINFSYDISKNAAGYNKWFFVTITTNM
MGNMMIYINGKLIDTIKVKELTGINFSKTITFQMNKIPNDNINMWIRDFY
IFAKELDDKDINILFNSLQYTNVVKDYWGNDLRYDKEYYMINVNYMNRYM
SKKGNGIVFNTRKNNNDFNEGYKIIIKRIRGNTNDTRVRGENVLYFNTTI
DNKQYSLGMYKPSRNLGTDLVPLGALDQPMDEIRKYGSFIIQPCNTFDYY
ASQLFLSSNATTNRLGILSIGSYSFKLGDDYWFNHEYLIPVIKIEHYASL
LESTSTHWVFVPAS
3D structure
PDB4isq Crystal Structures of Botulinum Neurotoxin DC in Complex with Its Protein Receptors Synaptotagmin I and II.
ChainC
Resolution2.65 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K906 I969
Catalytic site (residue number reindexed from 1) K44 I107
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C M1179 Y1180 K1181 P1182 N1185 L1190 V1191 Y1206 E1265 M309 Y310 K311 P312 N315 L320 V321 Y336 E395
Gene Ontology
Cellular Component
GO:0005576 extracellular region

View graph for
Cellular Component
External links
PDB RCSB:4isq, PDBe:4isq, PDBj:4isq
PDBsum4isq
PubMed23932591
UniProtQ9LBR1

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