Structure of PDB 4is1 Chain C

Receptor sequence
>4is1C (length=52) Species: 9606 (Homo sapiens) [Search protein sequence]
RECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLER
HH
3D structure
PDB4is1 New insights into DNA recognition by zinc fingers revealed by structural analysis of the oncoprotein ZNF217.
ChainC
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C F480 R481 Y485 H489 T492 Y506 Q510 T512 S513 Y516 F10 R11 Y15 H19 T22 Y36 Q40 T42 S43 Y46 PDBbind-CN: Kd=25nM
BS02 dna C Y484 K511 T512 R515 Y14 K41 T42 R45 PDBbind-CN: Kd=25nM
BS03 ZN C C501 C504 H517 H522 C31 C34 H47 H52
BS04 ZN C C473 C476 H489 H493 C3 C6 H19 H23
External links
PDB RCSB:4is1, PDBe:4is1, PDBj:4is1
PDBsum4is1
PubMed23436653
UniProtO75362|ZN217_HUMAN Zinc finger protein 217 (Gene Name=ZNF217)

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