Structure of PDB 4iin Chain C

Receptor sequence
>4iinC (length=238) Species: 85962 (Helicobacter pylori 26695) [Search protein sequence]
AMQFTGKNVLITGASKGIGAEIAKTLASMGLKVWINYRSNAEVADALKNE
LEEKGYKAAVIKFDAASESDFIEAIQTIVQSDGGLSYLVNNAGVVRDKLA
IKMKTEDFHHVIDNNLTSAFIGCREALKVMSKSRFGSVVNVASIIGERGN
MGQTNYSASKGGMIAMSKSFAYEGALRNIRFNSVTPGFIETKADYVKNIP
LNRLGSAKEVAEAVAFLLSDHSSYITGETLKVNGGLYM
3D structure
PDB4iin Crystal structure of a putative 3-oxoacyl-[acyl-carrier protein]reductase from Helicobacter pylori 26695 complexed with NAD+
ChainC
Resolution2.4 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) G16 S142 Y155 K159
Catalytic site (residue number reindexed from 1) G17 S143 Y156 K160
Enzyme Commision number 1.1.1.100: 3-oxoacyl-[acyl-carrier-protein] reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD C G12 G16 I17 R37 N90 A91 G92 V93 S142 Y155 K159 P185 G186 I188 G13 G17 I18 R38 N91 A92 G93 V94 S143 Y156 K160 P186 G187 I189
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004316 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
GO:0016491 oxidoreductase activity
GO:0051287 NAD binding
Biological Process
GO:0006633 fatty acid biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4iin, PDBe:4iin, PDBj:4iin
PDBsum4iin
PubMed
UniProtO25286

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