Structure of PDB 4i8c Chain C

Receptor sequence
>4i8cC (length=496) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
DEITTAWPVNVGPLNPHLYTPNQMFAQSMVYEPLVKYQADGSVIPWLAKS
WTHSEDGKTWTFTLRDDVKFSNGEPFDAEAAAENFRAVLDNRQRHAWLEL
ANQIVDVKALSKTELQITLKSAYYPFLQELALPRPFRFIAPSQFKNHETM
NGIKAPIGTGPWILQESKLNQYDVFVRNENYWGEKPAIKKITFNVIPDPT
TRAVAFETGDIDLLYGNEGLLPLDTFARFSQNPAYHTQLSQPIETVMLAL
NTAKAPTNELAVREALNYAVNKKSLIDNALYGTQQVADTLFAPSVPYANL
GLKPSQYDPQKAKALLEKAGWTLPAGKDIREKNGQPLRIELSFIGTDALS
KSMAEIIQADMRQIGADVSLIGEEESSIYARQRDGRFGMIFHRTWGAPYD
PHAFLSSMRVPSHADFQAQQGLADKPLIDKEIGEVLATHDETQRQALYRD
ILTRLHDEAVYLPISYISMMVVSKPELGNIPYAPIATEIPFEQIKP
3D structure
PDB4i8c The binding mode of Ni-((L)-His)(2) in NikA revealed by X-ray crystallography.
ChainC
Resolution2.503 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HIS C Y22 W100 R137 W398 Y402 H416 Y19 W97 R134 W395 Y399 H413
BS02 HIS C Y22 T23 R97 Y382 H416 Y19 T20 R94 Y379 H413
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0016151 nickel cation binding
GO:0020037 heme binding
GO:0046914 transition metal ion binding
GO:0051540 metal cluster binding
GO:1904680 peptide transmembrane transporter activity
Biological Process
GO:0015675 nickel cation transport
GO:0015833 peptide transport
GO:0050919 negative chemotaxis
GO:0055085 transmembrane transport
GO:0098716 nickel cation import across plasma membrane
Cellular Component
GO:0016020 membrane
GO:0030288 outer membrane-bounded periplasmic space
GO:0042597 periplasmic space
GO:0043190 ATP-binding cassette (ABC) transporter complex
GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing

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Molecular Function
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Cellular Component
External links
PDB RCSB:4i8c, PDBe:4i8c, PDBj:4i8c
PDBsum4i8c
PubMed23314594
UniProtP33590|NIKA_ECOLI Nickel-binding periplasmic protein (Gene Name=nikA)

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