Structure of PDB 4hur Chain C

Receptor sequence
>4hurC (length=210) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
DHGPDPENILPIKGNRNLQFIKPTITNENILVGEYSYYDSKRGESFEDQV
LYHYEVIGDKLIIGRFCSIGPGTTFIMNGANHRMDGSTYPFHLFRMGWEK
YMPSLKDLPLKGDIEIGNDVWIGRDVTIMPGVKIGDGAIIAAEAVVTKNV
APYSIVGGNPLKFIRKRFSDGVIEEWLALQWWNLDMKIINENLPFIINGD
IEMLKRKRKL
3D structure
PDB4hur Potential for Reduction of Streptogramin A Resistance Revealed by Structural Analysis of Acetyltransferase VatA.
ChainC
Resolution2.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ACO C Y57 A85 N86 K116 M134 T152 P165 Y52 A80 N81 K111 M129 T147 P160
BS02 ACO C S73 I74 G75 W126 I127 G128 R129 A146 A147 G162 I169 R170 S68 I69 G70 W121 I122 G123 R124 A141 A142 G157 I164 R165
Gene Ontology
Molecular Function
GO:0016740 transferase activity
GO:0016746 acyltransferase activity
Biological Process
GO:0046677 response to antibiotic

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Molecular Function
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Biological Process
External links
PDB RCSB:4hur, PDBe:4hur, PDBj:4hur
PDBsum4hur
PubMed25223995
UniProtP26839|VATA_STAAU Virginiamycin A acetyltransferase (Gene Name=vat)

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